Chemistry Professor Wei Kong and Statistics Professor Lan Xue will use their SciRIS grant to develop more effective mass spectrometry through inclusion of electron diffraction. With this addition, future mass spectrometers will be able to reveal not only the mass composition of an unknown species, but also the three-dimensional arrangement of the constituent atoms. This capability can change the paradigm of nanomaterial synthesis, allowing intelligent design and quality control of custom-made materials applicable in medical diagnostics and therapeutics, in energy harvesting and storage, and in catalysis.